Forget Botox. If you want to look and feel young, then what you should really be doing is swinging from the chandeliers. Regular sex in your youth, your middle years and beyond is the ultimate elixir of youth, says hormone and anti-ageing specialist Dr Cecilia Tregear. World-renowned Dr Tregear, who is based at the Wimpole […]
Continue reading →THYROID HORMONES INFLUENCE the cardiovascular system (1), and thyroid dysfunction may increase the risk of cardiovascular disease (2). Previous studies have shown that both hypo- and hyperthyroid disease may increase the risk of hypertension (2–5) and that hypertension related to hypothyroidism may be reversed after T4 treatment (6–8). Subclinical hypothyroid function, characterized by thyroid hormones […]
Continue reading →Exercise training (ET) and hormone replacement therapy (HRT) are both recognized influences on insulin action, but the influence of HRT on responses to ET has not been examined. In order to determine if HRT use provided additive benefits for the response of insulin action to ET, we evaluated the impact of HRT use on […]
Continue reading →Chronic heart failure (CHF) is a disease increasingly recognized as a health burden worldwide. An improvement in survival rate has been reported in CHF in the last decade (1), which should be ascribed mainly to therapeutic strategies targeted to the pathophysiological mechanisms sustaining the progression and worsening of the disease, mainly the prolonged neurohumoral […]
Continue reading →Abstract Background: Trials of testosterone therapy in aging men have demonstrated increases in fat-free mass (FFM) and skeletal muscle and decreases in fat mass (FM) but have not reported the impact of baseline body composition. Objective: The objective of the study was to determine the effect, in nonobese aging men with symptoms of androgen deficiency and low-normal […]
Continue reading →Abstract Context Prostate safety is a primary concern when aging men receive testosterone replacement therapy (TRT), but little information is available regarding the effects of TRT on prostate tissue in men. Objective To determine the effects of TRT on prostate tissue of aging men with low serum testosterone levels. Design, Setting, and Participants Randomized, double-blind, placebo-controlled trial of […]
Continue reading →Androgens are thought to play a role in the pathogenesis of prostate cancer. We evaluated androgen levels in 3 age-matched groups of men who were part of the Baltimore Longitudinal Study of Aging: 1) 16 men with no prostatic disease by urologic history and exam (control group); 2) 20 men with a histologic diagnosis of […]
Continue reading →A study of 930 men with coronary heart disease (CHD) showed that those who had testosterone deficiency were at increased risk of death. The overall prevalence of biochemical testosterone deficiency in the study population was 20.9% using a level of bioavailable testosterone levels below 2.6 nmol/L, 16.9% using a total testosterone level below 8.1 nmol/L, and 24% […]
Continue reading →Testosterone replacement therapy and prostate risks: where’s the beef? It has been part of the conventional medical wisdom for six decades that higher testosterone in some way increases the risk of prostate cancer. This belief is derived largely from the well-documented regression of prostate cancer in the face of surgical or pharmacological castration. However, there […]
Continue reading →Assessing progress in our understanding of prostate cancer etiology is difficult, although it is certainly clear that we have much to learn. Despite a substantial research investment spanning dozens of years, prostate cancer remains as enigmatic as it is burdensome. We know that increasing age, African American race, residence in a Western nation, and family […]
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